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Liver transplant procedure, step by step

A liver transplant has five stages: evaluation, donor work-up and approvals, surgery, intensive care and ward recovery. A living donor transplant is scheduled as soon as evaluation and the authorisation committee’s approval are complete.

Medically reviewed by Dr Vishal Kumar Chorasiya, MBBS, MS, FACS · Last updated 30 Sep 2026
Liver transplant surgery in progress at Yatharth Super Speciality Hospital

Key facts

  • Evaluation (1–2 weeks): Blood tests, CT or MRI of the liver, heart and lung checks, dental and infection screening, and meetings with the hepatologist, surgeon, anaesthetist, dietitian and counsellor.
  • Donor work-up and approval: The donor has blood tests, a CT scan to measure liver volume and anatomy, and a psychological assessment.
  • Surgery: The donor operation removes the right or left part of the liver.
  • Intensive care: Recipients spend about 3–5 days in the transplant ICU, then 7–10 days on the ward,, with close monitoring of blood flow to the new liver, kidney function and infection.
  • Ward and discharge: Most recipients go home about three weeks after surgery and donors after about a week, then attend frequent follow-up visits.
On this page

1. Evaluation (1–2 weeks)

Blood tests, CT or MRI of the liver, heart and lung checks, dental and infection screening, and meetings with the hepatologist, surgeon, anaesthetist, dietitian and counsellor.

2. Donor work-up and approval

The donor has blood tests, a CT scan to measure liver volume and anatomy, and a psychological assessment. The hospital authorisation committee reviews documents as required by law.

AASLT transplant team
The same team sees the recipient and donor through every stage

3. Surgery

The donor operation removes the right or left part of the liver. At the same time the recipient’s diseased liver is removed and the new graft is connected to the blood vessels and bile duct. The recipient operation usually takes 6–12 hours.

4. Intensive care

Recipients spend about 3–5 days in the transplant ICU, then 7–10 days on the ward,, with close monitoring of blood flow to the new liver, kidney function and infection.

5. Ward and discharge

Most recipients go home about three weeks after surgery and donors after about a week, then attend frequent follow-up visits. See life after transplant.

Types of liver transplant operation

Operation What happens Who it suits
Living donor (LDLT) Part of a healthy relative’s liver is transplanted Most adults and children in India
Deceased donor (DDLT) A whole liver from a brain-dead donor Patients on the state waiting list
Split liver One deceased donor liver is shared between an adult and a child Selected adult–child pairs
ABO-incompatible Donor and recipient blood groups differ; the recipient is prepared first When the only willing donor has a different blood group
Dual-graft Parts of two donors’ livers are transplanted Large recipients when one donor’s liver is not enough

Preparing for surgery

  • Stop alcohol and tobacco completely
  • Keep eating well: protein and calorie supplements as advised by the dietitian
  • Complete vaccinations (hepatitis B, pneumococcal, influenza) where time allows
  • Treat dental and other infections before the operation
  • Bring all reports, the list of medicines and the documents the coordinator asks for

Risks and how they are managed

Like all major surgery, a transplant has risks. The most important are bleeding, clots in the liver’s blood vessels, bile leaks, infection and rejection. Daily Doppler ultrasound, blood tests and early mobilisation help catch problems early. Interventional radiology and endoscopy can treat most bile duct and blood vessel problems without another operation.

Rejection is usually picked up on blood tests before you feel unwell, and is treated by adjusting medicines. This is why the follow-up visits in the first months matter.

Recovery timeline

When What to expect
Days 1–5 Transplant ICU; breathing tube usually removed within a day
Days 5–14 Ward: walking, eating, learning your medicines
Weeks 2–12 Frequent clinic visits and blood tests; light activity
Months 3–6 Back to most daily activities and often to work
After 6 months Visits spaced out; normal life with lifelong medicines

Frequently asked questions

Will the donor’s liver grow back?

Yes. Both the donor’s remaining liver and the recipient’s graft regrow close to full size within about 6–8 weeks.

How big is the scar?

Usually an inverted-L or Mercedes-type incision. Minimally invasive donor surgery may leave smaller scars where suitable.

How long does a liver transplant operation take?

The recipient operation usually takes 6–12 hours, depending on previous surgery, the size of the liver and the anatomy.

How long will I stay in hospital?

Usually 3–5 days in the transplant ICU, then 7–10 days on the ward. Donors usually stay about a week.

Is liver transplant surgery painful?

Pain is controlled with an epidural or pain pump in the first days, then tablets. Most patients are walking within two or three days.

When can I return to work?

Desk work is often possible after about three months; physically demanding work takes longer. The team advises you at follow-up.

What happens to my old liver?

The diseased liver is removed during the operation and sent for examination, which sometimes gives useful information, for example about a hidden cancer.

Dr Vishal Kumar Chorasiya
Reviewed byDr Vishal Kumar Chorasiya

Group Director – Liver Transplant, HPB, GI & Robotic Surgery, Yatharth Group of Hospitals. 18+ years in liver transplantation.

This page is for general information and is not a substitute for medical advice. Speak to the transplant team for a personal assessment.

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